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Effect of Sleep Disturbance on Efficacy of Esketamine in Treatment-Resistant Depression: Findings from Randomized Controlled Trials

PURPOSE: To evaluate the relationship of sleep disturbance to the antidepressant effects of esketamine. MATERIALS AND METHODS: Two double-blind, 4-week studies randomized adults with treatment-resistant depression (TRD) to placebo or esketamine nasal spray, each with newly initiated antidepressant....

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Detalles Bibliográficos
Autores principales: Borentain, Stephane, Williamson, David, Turkoz, Ibrahim, Popova, Vanina, McCall, William V, Mathews, Maju, Wiegand, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646953/
https://www.ncbi.nlm.nih.gov/pubmed/34880615
http://dx.doi.org/10.2147/NDT.S339090