FTLD‐TDP assemblies seed neoaggregates with subtype‐specific features via a prion‐like cascade

Morphologically distinct TDP‐43 aggregates occur in clinically different FTLD‐TDP subtypes, yet the mechanism of their emergence and contribution to clinical heterogeneity are poorly understood. Several lines of evidence suggest that pathological TDP‐43 follows a prion‐like cascade, but the molecula...

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Detalles Bibliográficos
Autores principales: De Rossi, Pierre, Lewis, Amanda J, Furrer, Johanna, De Vos, Laura, Demeter, Tomas, Zbinden, Aurélie, Zhong, Weijia, Wiersma, Vera I, Scialo, Carlo, Weber, Julien, Guo, Zhongning, Scaramuzza, Stefano, Di Fabrizio, Marta, Böing, Carolin, Castaño‐Díez, Daniel, Al‐Amoudi, Ashraf, Pérez‐Berlanga, Manuela, Lashley, Tammaryn, Stahlberg, Henning, Polymenidou, Magdalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647015/
https://www.ncbi.nlm.nih.gov/pubmed/34806807
http://dx.doi.org/10.15252/embr.202153877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647015/
https://www.ncbi.nlm.nih.gov/pubmed/34806807
http://dx.doi.org/10.15252/embr.202153877

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