The unfolded protein response links tumor aneuploidy to local immune dysregulation

Aneuploidy is a chromosomal abnormality associated with poor prognosis in many cancer types. Here, we tested the hypothesis that the unfolded protein response (UPR) mechanistically links aneuploidy and local immune dysregulation. Using a single somatic copy number alteration (SCNA) score inclusive o...

Descripción completa

Detalles Bibliográficos
Autores principales: Xian, Su, Dosset, Magalie, Almanza, Gonzalo, Searles, Stephen, Sahani, Paras, Waller, T Cameron, Jepsen, Kristen, Carter, Hannah, Zanetti, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647024/
https://www.ncbi.nlm.nih.gov/pubmed/34698427
http://dx.doi.org/10.15252/embr.202152509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647024/
https://www.ncbi.nlm.nih.gov/pubmed/34698427
http://dx.doi.org/10.15252/embr.202152509

Ejemplares similares