Cdc42‐Borg4‐Septin7 axis regulates HSC polarity and function

Aging of hematopoietic stem cells (HSCs) is caused by the elevated activity of the small RhoGTPase Cdc42 and an apolar distribution of proteins. Mechanisms by which Cdc42 activity controls polarity of HSCs are not known. Binder of RhoGTPases proteins (Borgs) are known effector proteins of Cdc42 that...

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Detalles Bibliográficos
Autores principales: Kandi, Ravinder, Senger, Katharina, Grigoryan, Ani, Soller, Karin, Sakk, Vadim, Schuster, Tanja, Eiwen, Karina, Menon, Manoj B, Gaestel, Matthias, Zheng, Yi, Florian, Maria Carolina, Geiger, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647144/
https://www.ncbi.nlm.nih.gov/pubmed/34661963
http://dx.doi.org/10.15252/embr.202152931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647144/
https://www.ncbi.nlm.nih.gov/pubmed/34661963
http://dx.doi.org/10.15252/embr.202152931

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