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PLK1‐dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV‐infected mice
While Epstein–Barr virus (EBV) establishes a life‐long latent infection in apparently healthy human immunocompetent hosts, immunodeficient individuals are at particular risk to develop lymphoproliferative B‐cell malignancies caused by EBV. A key EBV protein is the transcription factor EBV nuclear an...
Autores principales: | Zhang, Xiang, Schuhmachers, Patrick, Mourão, André, Giansanti, Piero, Murer, Anita, Thumann, Sybille, Kuklik‐Roos, Cornelia, Beer, Sophie, Hauck, Stefanie M, Hammerschmidt, Wolfgang, Küppers, Ralf, Kuster, Bernhard, Raab, Monika, Strebhardt, Klaus, Sattler, Michael, Münz, Christian, Kempkes, Bettina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647151/ https://www.ncbi.nlm.nih.gov/pubmed/34605140 http://dx.doi.org/10.15252/embr.202153007 |
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