Development and Validation of an HPLC-UV Method for Quantitation of Linezolid: Application to Resistance Study Using in vitro PK/PD Model

BACKGROUND: Linezolid (LNZ), an oxazolidinone antibiotic, has 100% oral bioavailability and favorable activities against gram-positive pathogens. The in vitro PK/PD model was developed based on concentrations obtained with routine doses in humans can be used to guide dose optimization in the clinic....

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Detalles Bibliográficos
Autores principales: Yang, Guang, Yan, Yisong, Mao, Jun, Liu, Huiping, Chen, Mingtao, Zhang, Na, Li, Yaowen, Gu, Jiangjun, Huang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647170/
https://www.ncbi.nlm.nih.gov/pubmed/34880634
http://dx.doi.org/10.2147/IDR.S343200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647170/
https://www.ncbi.nlm.nih.gov/pubmed/34880634
http://dx.doi.org/10.2147/IDR.S343200

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