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Inhibition of LC3-associated phagocytosis in COPD and in response to cigarette smoke

INTRODUCTION/RATIONALE: In chronic obstructive pulmonary disease (COPD), defective macrophage phagocytic clearance of cells undergoing apoptosis by efferocytosis may lead to secondary necrosis of the uncleared cells and contribute to airway inflammation. The precise mechanisms for this phenomenon re...

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Detalles Bibliográficos
Autores principales: Asare, Patrick F., Tran, Hai B., Hurtado, Plinio R., Perkins, Griffith B., Nguyen, Phan, Jersmann, Hubertus, Roscioli, Eugene, Hodge, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647217/
https://www.ncbi.nlm.nih.gov/pubmed/34852704
http://dx.doi.org/10.1177/17534666211039769