Optogenetically controlled human functional motor endplate for testing botulinum neurotoxins

BACKGROUND: The lack of physiologically relevant and predictive cell-based assays is one of the major obstacles for testing and developing botulinum neurotoxins (BoNTs) therapeutics. Human-induced pluripotent stem cells (hiPSCs)-derivatives now offer the opportunity to improve the relevance of cellu...

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Detalles Bibliográficos
Autores principales: de Lamotte, Juliette Duchesne, Polentes, Jérôme, Roussange, Florine, Lesueur, Léa, Feurgard, Pauline, Perrier, Anselme, Nicoleau, Camille, Martinat, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647380/
https://www.ncbi.nlm.nih.gov/pubmed/34865655
http://dx.doi.org/10.1186/s13287-021-02665-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647380/
https://www.ncbi.nlm.nih.gov/pubmed/34865655
http://dx.doi.org/10.1186/s13287-021-02665-3

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