Single cell sequencing analysis identifies genetics-modulated ORMDL3(+) cholangiocytes having higher metabolic effects on primary biliary cholangitis

BACKGROUND: Primary biliary cholangitis (PBC) is a classical autoimmune disease, which is highly influenced by genetic determinants. Many genome-wide association studies (GWAS) have reported that numerous genetic loci were significantly associated with PBC susceptibility. However, the effects of gen...

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Detalles Bibliográficos
Autores principales: Xiang, Bingyu, Deng, Chunyu, Qiu, Fei, Li, Jingjing, Li, Shanshan, Zhang, Huifang, Lin, Xiuli, Huang, Yukuan, Zhou, Yijun, Su, Jianzhong, Lu, Mingqin, Ma, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647381/
https://www.ncbi.nlm.nih.gov/pubmed/34872583
http://dx.doi.org/10.1186/s12951-021-01154-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647381/
https://www.ncbi.nlm.nih.gov/pubmed/34872583
http://dx.doi.org/10.1186/s12951-021-01154-2

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