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Single cell sequencing analysis identifies genetics-modulated ORMDL3(+) cholangiocytes having higher metabolic effects on primary biliary cholangitis

BACKGROUND: Primary biliary cholangitis (PBC) is a classical autoimmune disease, which is highly influenced by genetic determinants. Many genome-wide association studies (GWAS) have reported that numerous genetic loci were significantly associated with PBC susceptibility. However, the effects of gen...

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Detalles Bibliográficos
Autores principales:	Xiang, Bingyu, Deng, Chunyu, Qiu, Fei, Li, Jingjing, Li, Shanshan, Zhang, Huifang, Lin, Xiuli, Huang, Yukuan, Zhou, Yijun, Su, Jianzhong, Lu, Mingqin, Ma, Yunlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647381/ https://www.ncbi.nlm.nih.gov/pubmed/34872583 http://dx.doi.org/10.1186/s12951-021-01154-2

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