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Preclinical evaluation of strasseriolides A–D, potent antiplasmodial macrolides isolated from Strasseria geniculata CF-247,251

BACKGROUND: Malaria is a global health problem for which novel therapeutic compounds are needed. To this end, a recently published novel family of antiplasmodial macrolides, strasseriolides A–D, was herein subjected to in vivo efficacy studies and preclinical evaluation in order to identify the most...

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Detalles Bibliográficos
Autores principales: Annang, Frederick, Pérez-Moreno, Guiomar, Díaz, Caridad, González-Menéndez, Victor, de Pedro Montejo, Nuria, del Palacio, José Pérez, Sánchez, Paula, Tanghe, Scott, Rodriguez, Ana, Pérez-Victoria, Ignacio, Cantizani, Juan, Ruiz-Pérez, Luis M., Genilloud, Olga, Reyes, Fernando, Vicente, Francisca, González-Pacanowska, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647499/
https://www.ncbi.nlm.nih.gov/pubmed/34865639
http://dx.doi.org/10.1186/s12936-021-03993-8