Immunization with short peptide particles reveals a functional CD8(+) T-cell neoepitope in a murine renal carcinoma model

BACKGROUND: Induction of CD8(+) T cells that recognize immunogenic, mutated protein fragments in the context of major histocompatibility class I (MHC-I) is a pressing challenge for cancer vaccine development. METHODS: Using the commonly used murine renal adenocarcinoma RENCA cancer model, MHC-I rest...

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Detalles Bibliográficos
Autores principales: He, Xuedan, Zhou, Shiqi, Dolan, Melissa, Shi, Yuhao, Wang, Jianxin, Quinn, Breandan, Jahagirdar, Dushyant, Huang, Wei-Chiao, Tsuji, Moriya, Pili, Roberto, Ito, Fumito, Ortega, Joaquin, Abrams, Scott I, Ebos, John M L, Lovell, Jonathan F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647534/
https://www.ncbi.nlm.nih.gov/pubmed/34862254
http://dx.doi.org/10.1136/jitc-2021-003101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647534/
https://www.ncbi.nlm.nih.gov/pubmed/34862254
http://dx.doi.org/10.1136/jitc-2021-003101

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