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A protocol for the systematic review and meta-analysis of thigmotactic behaviour in the open field test in rodent models associated with persistent pain

OBJECTIVE: Thigmotaxis is an innate predator avoidance behaviour of rodents and is enhanced when animals are under stress. It is characterised by the preference of a rodent to seek shelter, rather than expose itself to the aversive open area. The behaviour has been proposed to be a measurable constr...

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Detalles Bibliográficos
Autores principales: Zhang, Xue Ying, Vollert, Jan, Sena, Emily S, Rice, Andrew SC, Soliman, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647568/
https://www.ncbi.nlm.nih.gov/pubmed/35047702
http://dx.doi.org/10.1136/bmjos-2020-100135