Decoding the function of bivalent chromatin in development and cancer

Bivalent chromatin is characterized by the simultaneous presence of H3K4me3 and H3K27me3, histone modifications generally associated with transcriptionally active and repressed chromatin, respectively. Prevalent in embryonic stem cells (ESCs), bivalency is postulated to poise/prime lineage-controlli...

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Detalles Bibliográficos
Autores principales: Kumar, Dhirendra, Cinghu, Senthilkumar, Oldfield, Andrew J., Yang, Pengyi, Jothi, Raja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647824/
https://www.ncbi.nlm.nih.gov/pubmed/34667120
http://dx.doi.org/10.1101/gr.275736.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647824/
https://www.ncbi.nlm.nih.gov/pubmed/34667120
http://dx.doi.org/10.1101/gr.275736.121

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