Individualized VDJ recombination predisposes the available Ig sequence space

The process of recombination between variable (V), diversity (D), and joining (J) immunoglobulin (Ig) gene segments determines an individual's naive Ig repertoire and, consequently, (auto)antigen recognition. VDJ recombination follows probabilistic rules that can be modeled statistically. So fa...

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Detalles Bibliográficos
Autores principales: Slabodkin, Andrei, Chernigovskaya, Maria, Mikocziova, Ivana, Akbar, Rahmad, Scheffer, Lonneke, Pavlović, Milena, Bashour, Habib, Snapkov, Igor, Mehta, Brij Bhushan, Weber, Cédric R., Gutierrez-Marcos, Jose, Sollid, Ludvig M., Haff, Ingrid Hobæk, Sandve, Geir Kjetil, Robert, Philippe A., Greiff, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647828/
https://www.ncbi.nlm.nih.gov/pubmed/34815307
http://dx.doi.org/10.1101/gr.275373.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647828/
https://www.ncbi.nlm.nih.gov/pubmed/34815307
http://dx.doi.org/10.1101/gr.275373.121

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