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Central role of intestinal epithelial glucocorticoid receptor in alcohol‐ and corticosterone‐induced gut permeability and systemic response

Corticosterone, the stress hormone, exacerbates alcohol‐associated tissue injury, but the mechanism involved is unknown. We examined the role of the glucocorticoid receptor (GR) in corticosterone‐mediated potentiation of alcohol‐induced gut barrier dysfunction and systemic response. Hepatocyte‐speci...

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Detalles Bibliográficos
Autores principales: Shukla, Pradeep K., Meena, Avtar S., Pierre, Joseph F., Rao, RadhaKrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647846/
https://www.ncbi.nlm.nih.gov/pubmed/34861075
http://dx.doi.org/10.1096/fj.202101424R