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Exposure to varenicline protects against locomotor alteration in a MPTP mouse model of Parkinson's disease

The beneficial effects of drugs that act via nicotinic acetylcholine receptors (nAChRs) on Parkinson's disease (PD) symptomatology may explain the negative correlation between cigarette smoking and risk of this neurological condition. Varenicline, an α4β2 nAChR partial agonist approved for smok...

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Detalles Bibliográficos
Autores principales: Ribeiro-Carvalho, A., Leal-Rocha, P.H., Isnardo-Fernandes, J., Araújo, U.C., Abreu-Villaça, Y., Filgueiras, C.C., Manhães, A.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647902/
https://www.ncbi.nlm.nih.gov/pubmed/34878065
http://dx.doi.org/10.1590/1414-431X2021e11679