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Exposure to varenicline protects against locomotor alteration in a MPTP mouse model of Parkinson's disease
The beneficial effects of drugs that act via nicotinic acetylcholine receptors (nAChRs) on Parkinson's disease (PD) symptomatology may explain the negative correlation between cigarette smoking and risk of this neurological condition. Varenicline, an α4β2 nAChR partial agonist approved for smok...
Autores principales: | Ribeiro-Carvalho, A., Leal-Rocha, P.H., Isnardo-Fernandes, J., Araújo, U.C., Abreu-Villaça, Y., Filgueiras, C.C., Manhães, A.C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647902/ https://www.ncbi.nlm.nih.gov/pubmed/34878065 http://dx.doi.org/10.1590/1414-431X2021e11679 |
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