The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2‐deficient leukoencephalopathy

The contribution of microglia in neurological disorders is emerging as a leading disease driver rather than a consequence of pathology. RNAseT2‐deficient leukoencephalopathy is a severe childhood white matter disorder affecting patients in their first year of life and mimicking a cytomegalovirus bra...

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Detalles Bibliográficos
Autores principales: Hamilton, Noémie, Rutherford, Holly A., Petts, Jessica J., Isles, Hannah M., Weber, Thomas, Henneke, Marco, Gärtner, Jutta, Dunning, Mark J., Renshaw, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647916/
https://www.ncbi.nlm.nih.gov/pubmed/32212285
http://dx.doi.org/10.1002/glia.23829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647916/
https://www.ncbi.nlm.nih.gov/pubmed/32212285
http://dx.doi.org/10.1002/glia.23829

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