Effect of quercetin on the pharmacokinetics of selexipag and its active metabolite in beagles

CONTEXT: As an inhibitor cytochrome P450 family 2 subfamily C polypeptide 8 (CYP2C8), quercetin is a naturally occurring flavonoid with its glycosides consumed at least 100 mg per day in food. However, it is still unknown whether quercetin and selexipag interact. OBJECTIVE: The study investigated th...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Shun-bin, Gu, Er-min, Chen, Yu-ao, Zhou, Shi-chen, Fan, Chen, Xu, Ren-ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648015/
https://www.ncbi.nlm.nih.gov/pubmed/34860644
http://dx.doi.org/10.1080/13880209.2021.2005636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648015/
https://www.ncbi.nlm.nih.gov/pubmed/34860644
http://dx.doi.org/10.1080/13880209.2021.2005636

Ejemplares similares