IMB-XMA0038, a new inhibitor targeting aspartate-semialdehyde dehydrogenase of Mycobacterium tuberculosis

The emergence of drug-resistant tuberculosis (TB) constitutes a major challenge to TB control programmes. There is an urgent need to develop effective anti-TB drugs with novel mechanisms of action. Aspartate-semialdehyde dehydrogenase (ASADH) is the second enzyme in the aspartate metabolic pathway....

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Detalles Bibliográficos
Autores principales: Wang, Xiao, Yang, Ruifang, Liu, Sihan, Guan, Yan, Xiao, Chunling, Li, Chuanyou, Meng, Jianzhou, Pang, Yu, Liu, Yishuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Drug Resistance and Novel Antimicrobial Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648042/
https://www.ncbi.nlm.nih.gov/pubmed/34779708
http://dx.doi.org/10.1080/22221751.2021.2006578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648042/
https://www.ncbi.nlm.nih.gov/pubmed/34779708
http://dx.doi.org/10.1080/22221751.2021.2006578

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