Gap Junctional Coupling Between Retinal Astrocytes Exacerbates Neuronal Damage in Ischemia-Reperfusion Injury

PURPOSE: Retinal astrocytes abundantly express connexin 43 (Cx43), a transmembrane protein that forms gap junction (GJ) channels and unopposed hemichannels. While it is well established that Cx43 is upregulated in retinal injuries, it is unclear whether astrocytic Cx43 plays a role in retinal gangli...

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Detalles Bibliográficos
Autores principales: Toychiev, Abduqodir H., Batsuuri, Khulan, Srinivas, Miduturu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648063/
https://www.ncbi.nlm.nih.gov/pubmed/34846518
http://dx.doi.org/10.1167/iovs.62.14.27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648063/
https://www.ncbi.nlm.nih.gov/pubmed/34846518
http://dx.doi.org/10.1167/iovs.62.14.27

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