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NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1

In mammals, the circadian clock coordinates cell physiological processes including inflammation. Recent studies suggested a crosstalk between these two pathways. However, the mechanism of how inflammation affects the clock is not well understood. Here, we investigated the role of the proinflammatory...

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Detalles Bibliográficos
Autores principales: Shen, Yang, Endale, Mehari, Wang, Wei, Morris, Andrew R., Francey, Lauren J., Harold, Rachel L., Hammers, David W., Huo, Zhiguang, Partch, Carrie L., Hogenesch, John B., Wu, Zhao-Hui, Liu, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648109/
https://www.ncbi.nlm.nih.gov/pubmed/34807912
http://dx.doi.org/10.1371/journal.pgen.1009933