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CBMS-10 Methionine metabolism closely related with self-renew, pluripotency and cell death in GICs through modification of cholesterol biosynthesis and ribosomal RNA

Glioma initiating cells (GICs) are the source of glioma cells that have the ability to self-renew and pluripotency, which are treatment-resistant, starting point for relapse and eventual death despite multimodality therapy. Since high accumulation is observed in 11cMet-PET at the time of recurrence,...

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Detalles Bibliográficos
Autores principales: Yokogami, Kiyotaka, Nakatake, Yasutaka, Watanabe, Takashi, Mizuguchi, Asako, Yamashita, Shinji, Takeshima, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648199/
http://dx.doi.org/10.1093/noajnl/vdab159.009