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CBMS-5 One-carbon metabolism protect glioma cells under glutamine starvation through upregulation of MTHFD2

Cancer cells optimize nutrient utilization to supply energetic and biosynthetic pathways. However, less is known about how cancer cells exhibit metabolic flexibility to sustain cell growth and survival from nutrient starvation. Here, we find that serine and glycine levels were higher in low-nutrient...

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Detalles Bibliográficos
Autores principales: Tanaka, Kazuhiro, Nagashima, Hiroaki, Uno, Takiko, Fujita, Yuichi, Iwahashi, Hirofumi, Sasayama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648210/
http://dx.doi.org/10.1093/noajnl/vdab159.007