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ET-9 Development of photosensitive antibodies for near-infrared light immunotherapy targeting EGFR and IL13Rα2 of malignant gliomas and investigation of their photodynamic cytotoxic activity in vitro

Introduction: Near-Infrared Photoimmunotherapy (NIR-PIT) is a recently developed hybrid cancer therapy based on photodynamic cytotoxicity and anti-tumor immunopotentiation, utilizing a photosensitive antibody drug (PSAD). A global Phase III trial of NIR-PIT with an anti-EGFR-PSAD in patients with re...

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Detalles Bibliográficos
Autores principales: Nonoguchi, Naosuke, Kambara, Akihiro, Kimura, Seigo, Kawabata, Shinji, Yagi, Ryokichi, Ikeda, Naokado, Furuse, Motomasa, Wanibuchi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648211/
http://dx.doi.org/10.1093/noajnl/vdab159.019