Cargando…

ET-9 Development of photosensitive antibodies for near-infrared light immunotherapy targeting EGFR and IL13Rα2 of malignant gliomas and investigation of their photodynamic cytotoxic activity in vitro

Introduction: Near-Infrared Photoimmunotherapy (NIR-PIT) is a recently developed hybrid cancer therapy based on photodynamic cytotoxicity and anti-tumor immunopotentiation, utilizing a photosensitive antibody drug (PSAD). A global Phase III trial of NIR-PIT with an anti-EGFR-PSAD in patients with re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nonoguchi, Naosuke, Kambara, Akihiro, Kimura, Seigo, Kawabata, Shinji, Yagi, Ryokichi, Ikeda, Naokado, Furuse, Motomasa, Wanibuchi, Masahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Supplement Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648211/ http://dx.doi.org/10.1093/noajnl/vdab159.019

Ejemplares similares

STMO-07 Adverse events related to the glioblastoma surgery and their perioperative management in our hospital
por: Kashiwagi, Hideki, et al.
Publicado: (2020)

Long-Term Prognosis of Cognitive Function in Patients With Idiopathic Normal Pressure Hydrocephalus After Shunt Surgery
por: Kambara, Akihiro, et al.
Publicado: (2021)

Occult neurohypophyseal germinoma discovered during the course of long-term diabetes insipidus: illustrative case
por: Yamada, Hironori, et al.
Publicado: (2023)

Chronic expanding pituitary hematoma with calcification resulting from pituitary adenoma: illustrative case
por: Takagi, Fugen, et al.
Publicado: (2023)

Influence of surgical position and registration methods on clinical accuracy of navigation systems in brain tumor surgery
por: Furuse, Motomasa, et al.
Publicado: (2023)

Frameless Stereotactic Biopsy with Intraoperative Computed Tomography “Assessment of Efficacy and Real Target Registration Error”
por: IKEDA, Naokado, et al.
Publicado: (2022)

Bilateral Posterolateral Sulcus Approach for the Removal of Spinal Intramedullary Metastatic Adenocarcinoma: A Technical Case Report
por: TSUJINO, Kohei, et al.
Publicado: (2022)

Anatomical Limitation of Posterior Spinal Myelotomy for Intramedullary Hemorrhage Associated with Ependymoma or Cavernous Malformation of the High Cervical Spine
por: TSUJINO, Kohei, et al.
Publicado: (2022)

Treatment Outcomes of 94 Cases of Pipeline Embolization Device in a Single Center: Predictive Factors of Incomplete Aneurysm Occlusion
por: Hiramatsu, Ryo, et al.
Publicado: (2023)

ET-5 Biological effects of simultaneous use of multiple drugs in neutron capture therapy using rat brain tumor model
por: Kawabata, Shinji, et al.
Publicado: (2021)

Characteristic and Management of Symptomatic Septum Pellucidum Cyst in Extreme Elderly Patient: Case Report and Literature Review
por: IKEDA, Naokado, et al.
Publicado: (2022)

Occult Germinoma of the Intramedullary Spinal Cord: A Case Report
por: HOSHIMARU, Takumi, et al.
Publicado: (2023)

Increasing C-reactive protein levels in a patient with glioblastoma with lymph node metastasis: a case report
por: Kanemitsu, Takuya, et al.
Publicado: (2023)

NI-04 WHICH RADIOLOGICAL IMAGING IS BEST TO DISCRIMINATE RADIATION NECROSIS FROM TUMOR PROGRESSION? - SUBANALYSIS OF SYSTEMATIC REVIEW FOR RADIOLOGICAL DIAGNOSIS OF RADIATION NECROSIS
por: Furuse, Motomasa, et al.
Publicado: (2019)

Evaluation of the Effectiveness of the Tap Test by Combining the Use of Functional Gait Assessment and Global Rating of Change
por: Kameda, Masahiro, et al.
Publicado: (2022)

Corrigendum: Evaluation of the Effectiveness of the Tap Test by Combining the Use of Functional Gait Assessment and Global Rating of Change
por: Kameda, Masahiro, et al.
Publicado: (2022)

Pituitary stone resulting in visual dysfunction and spontaneous rhinorrhea in nonfunctioning pituitary adenoma: illustrative case
por: Kanemitsu, Takuya, et al.
Publicado: (2021)

Using virtual lines of navigation for a successful transcortical approach
por: Omura, Naoki, et al.
Publicado: (2023)

Fluoroscopic-Guided Paramedian Approach for Lumbar Catheter Placement in Cerebrospinal Fluid Shunting: Assessment of Safety and Accuracy
por: Tucker, Adam, et al.
Publicado: (2019)

Multimodal Management of Combined Posterior and Anterior Surgical Approach and Postoperative Pharmacological Therapy for Giant Cell Tumor of the Cervical Spine Encasing the Vertebral Artery: A Technical Case Report
por: TSUJI, Yuichiro, et al.
Publicado: (2022)

Brain abscess caused by Nocardia thailandica infection in systemic lupus erythematosus patient with steroid therapy
por: Yagi, Ryokichi, et al.
Publicado: (2022)

Radiological diagnosis of brain radiation necrosis after cranial irradiation for brain tumor: a systematic review
por: Furuse, Motomasa, et al.
Publicado: (2019)

Actin Alpha 2, Smooth Muscle (ACTA2) Is Involved in the Migratory Potential of Malignant Gliomas, and Its Increased Expression at Recurrence Is a Significant Adverse Prognostic Factor
por: Hoshimaru, Takumi, et al.
Publicado: (2023)

ML-07 High expression of PD-L1 on tumor-associated macrophage is a predictive factor for favorable prognosis in PCNSL
por: Furuse, Motomasa, et al.
Publicado: (2020)

CBMS-10 INFLUENCE OF HYPOXIA ON PHOTODYNAMIC THERAPY WITH 5-AMINOLEVULINIC ACID FOR MALIGNANT GLIOMA STEM CELLS
por: Nonoguchi, Naosuke, et al.
Publicado: (2022)

CBMS-9 INFLUENCE OF HYPOXIA ON PHOTODYNAMIC THERAPY WITH 5-AMINOLEVULINIC ACID FOR MALIGNANT GLIOMA STEM CELLS
por: Nonoguchi, Naosuke, et al.
Publicado: (2022)

ACT-3 Reactor-based boron neutron capture therapy with add-on bevacizumab for recurrent malignant glioma: The final report
por: Furuse, Motomasa, et al.
Publicado: (2021)

Surgical strategy for tuberculous brain abscess with dural infiltration: A case report
por: Hoshimaru, Takumi, et al.
Publicado: (2022)

Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas
por: Furuse, Motomasa, et al.
Publicado: (2015)

A Case of a Ruptured Microaneurysm at the Tip of the Basilar Artery With Right Abducens Nerve Palsy at the Time of the Initial Rupture and Rerupture During an Outpatient Follow-Up
por: Kimura, Seigo, et al.
Publicado: (2022)

Facial Spasm Caused by Compression of the Distal Portion of the Facial Nerve by the Anterior Inferior Cerebellar Artery, Resulting in Delayed Peripheral Facial Nerve Palsy: A Case Report
por: Kimura, Seigo, et al.
Publicado: (2023)

Intraoperative 5-aminolevulinic acid-induced photodynamic diagnosis of metastatic brain tumors with histopathological analysis
por: Yagi, R., et al.
Publicado: (2017)

The roles of platelet-derived growth factors and their receptors in brain radiation necrosis
por: Miyata, Tomo, et al.
Publicado: (2014)

Chronic pathophysiological changes in the normal brain parenchyma caused by radiotherapy accelerate glioma progression
por: Tsuji, Yuichiro, et al.
Publicado: (2021)

5-Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapy
por: Fukumura, Masao, et al.
Publicado: (2023)

A Case of Fulminant Fat Embolism Syndrome With Very Early Onset After Femoral Neck and Sacral Fractures
por: Kimura, Seigo, et al.
Publicado: (2023)

Inflammation as well as angiogenesis may participate in the pathophysiology of brain radiation necrosis
por: Yoritsune, Erina, et al.
Publicado: (2014)

Evaluation of the Effectiveness of Boron Neutron Capture Therapy with Iodophenyl-Conjugated closo-Dodecaborate on a Rat Brain Tumor Model
por: Fujikawa, Yoshiki, et al.
Publicado: (2023)

Rupture of a Left Posterior Inferior Cerebellar Artery Aneurysm with a Vertebral Artery Originating from the Aorta
por: Kimura, Seigo, et al.
Publicado: (2020)

NI-04 Evaluation of post boron neutron capture therapy for recurrent meningioma using fluoride-labeled boronophenylalanine PET
por: Takai, Satoshi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_geibogtckvuu25u61j11ikrmb6