Control of neurotransmitter release by two distinct membrane-binding faces of the Munc13-1 C(1)C(2)B region

Munc13-1 plays a central role in neurotransmitter release through its conserved C-terminal region, which includes a diacyglycerol (DAG)-binding C(1) domain, a Ca(2+)/PIP(2)-binding C(2)B domain, a MUN domain and a C(2)C domain. Munc13-1 was proposed to bridge synaptic vesicles to the plasma membrane...

Descripción completa

Detalles Bibliográficos
Autores principales: Camacho, Marcial, Quade, Bradley, Trimbuch, Thorsten, Xu, Junjie, Sari, Levent, Rizo, Josep, Rosenmund, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648301/
https://www.ncbi.nlm.nih.gov/pubmed/34779770
http://dx.doi.org/10.7554/eLife.72030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648301/
https://www.ncbi.nlm.nih.gov/pubmed/34779770
http://dx.doi.org/10.7554/eLife.72030

Ejemplares similares