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Control of neurotransmitter release by two distinct membrane-binding faces of the Munc13-1 C(1)C(2)B region
Munc13-1 plays a central role in neurotransmitter release through its conserved C-terminal region, which includes a diacyglycerol (DAG)-binding C(1) domain, a Ca(2+)/PIP(2)-binding C(2)B domain, a MUN domain and a C(2)C domain. Munc13-1 was proposed to bridge synaptic vesicles to the plasma membrane...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648301/ https://www.ncbi.nlm.nih.gov/pubmed/34779770 http://dx.doi.org/10.7554/eLife.72030 |