Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells

Lipidoid nanoparticles (LNPs) are the delivery platform in Onpattro, the first FDA-approved siRNA drug. LNPs are also the carriers in the Pfizer-BioNTech and Moderna COVID-19 mRNA vaccines. While these applications have demonstrated that LNPs effectively deliver nucleic acids to hepatic and muscle c...

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Detalles Bibliográficos
Autores principales: Khare, Purva, Dave, Kandarp M., Kamte, Yashika S., Manoharan, Muthiah A., O’Donnell, Lauren A., Manickam, Devika S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648339/
https://www.ncbi.nlm.nih.gov/pubmed/34873640
http://dx.doi.org/10.1208/s12248-021-00653-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648339/
https://www.ncbi.nlm.nih.gov/pubmed/34873640
http://dx.doi.org/10.1208/s12248-021-00653-2

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