Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer's Disease Mutations

Alzheimer's disease manifests itself in brain tissue by neuronal death, due to aggregation of β-amyloid, produced by senile plaques, and hyperphosphorylation of the tau protein, which produces neurofibrillary tangles. One of the genetic markers of the disease is the gene that translates the pre...

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Detalles Bibliográficos
Autores principales: Soto-Ospina, Alejandro, Araque Marín, Pedronel, Bedoya, Gabriel de Jesús, Villegas Lanau, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648483/
https://www.ncbi.nlm.nih.gov/pubmed/34881055
http://dx.doi.org/10.1155/2021/9542038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648483/
https://www.ncbi.nlm.nih.gov/pubmed/34881055
http://dx.doi.org/10.1155/2021/9542038

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