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Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer's Disease Mutations

Alzheimer's disease manifests itself in brain tissue by neuronal death, due to aggregation of β-amyloid, produced by senile plaques, and hyperphosphorylation of the tau protein, which produces neurofibrillary tangles. One of the genetic markers of the disease is the gene that translates the pre...

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Detalles Bibliográficos
Autores principales:	Soto-Ospina, Alejandro, Araque Marín, Pedronel, Bedoya, Gabriel de Jesús, Villegas Lanau, Andrés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648483/ https://www.ncbi.nlm.nih.gov/pubmed/34881055 http://dx.doi.org/10.1155/2021/9542038

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