Phase Ib study on the humanized anti-CCR4 antibody, KW-0761, in advanced solid tumors

Tregs infiltrate tumors and inhibit antitumor immunity. KW-0761 (Mogamulizumab) is a humanized anti-CCR4 monoclonal antibody that could eliminate activated Tregs with high immunosuppressive activity that express CCR4. In this phase Ib trial, KW-0761 was used as a cancer immunotherapeutic reagent to...

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Detalles Bibliográficos
Autores principales: Saito, Takuro, Kurose, Koji, Kojima, Takashi, Funakoshi, Takeru, Sato, Eiichi, Nishikawa, Hiroyoshi, Nakajima, Jun, Seto, Yasuyuki, Kakimi, Kazuhiro, Iida, Shinsuke, Doki, Yuichiro, Oka, Mikio, Ueda, Ryuzo, Wada, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nagoya University 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648528/
https://www.ncbi.nlm.nih.gov/pubmed/34916725
http://dx.doi.org/10.18999/nagjms.83.4.827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648528/
https://www.ncbi.nlm.nih.gov/pubmed/34916725
http://dx.doi.org/10.18999/nagjms.83.4.827

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