Drug combination screening as a translational approach toward an improved drug therapy for chordoma

PURPOSE: Drug screening programmes have revealed epidermal growth factor receptor inhibitors (EGFR(i)s) as promising therapeutics for chordoma, an orphan malignant bone tumour, in the absence of a known genetic driver. Concurrently, the irreversible EGFR(i) afatinib (Giotrif®) is being evaluated in...

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Detalles Bibliográficos
Autores principales: Scheipl, Susanne, Barnard, Michelle, Lohberger, Birgit, Zettl, Richard, Brcic, Iva, Liegl-Atzwanger, Bernadette, Rinner, Beate, Meindl, Claudia, Fröhlich, Eleonore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648636/
https://www.ncbi.nlm.nih.gov/pubmed/34550531
http://dx.doi.org/10.1007/s13402-021-00632-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648636/
https://www.ncbi.nlm.nih.gov/pubmed/34550531
http://dx.doi.org/10.1007/s13402-021-00632-x

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