Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer

A germline 29.5-kb deletion variant removes the 3’ end of the APOBEC3A gene and a large part of APOBEC3B, creating a hybrid gene that has been linked to increased APOBEC3 activity and DNA damage in human cancers. We genotyped the APOBEC3A/B deletion in hospital-based samples of 1398 Norwegian epithe...

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Detalles Bibliográficos
Autores principales: Gansmo, Liv B., Sofiyeva, Nigar, Bjørnslett, Merete, Romundstad, Pål, Hveem, Kristian, Vatten, Lars, Dørum, Anne, Lønning, Per E., Knappskog, Stian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648731/
https://www.ncbi.nlm.nih.gov/pubmed/34873230
http://dx.doi.org/10.1038/s41598-021-02820-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648731/
https://www.ncbi.nlm.nih.gov/pubmed/34873230
http://dx.doi.org/10.1038/s41598-021-02820-z

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