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Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
A germline 29.5-kb deletion variant removes the 3’ end of the APOBEC3A gene and a large part of APOBEC3B, creating a hybrid gene that has been linked to increased APOBEC3 activity and DNA damage in human cancers. We genotyped the APOBEC3A/B deletion in hospital-based samples of 1398 Norwegian epithe...
Autores principales: | Gansmo, Liv B., Sofiyeva, Nigar, Bjørnslett, Merete, Romundstad, Pål, Hveem, Kristian, Vatten, Lars, Dørum, Anne, Lønning, Per E., Knappskog, Stian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648731/ https://www.ncbi.nlm.nih.gov/pubmed/34873230 http://dx.doi.org/10.1038/s41598-021-02820-z |
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