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Zipper head mechanism of telomere synthesis by human telomerase

Telomerase, a multi-subunit ribonucleoprotein complex, is a unique reverse transcriptase that catalyzes the processive addition of a repeat sequence to extend the telomere end using a short fragment of its own RNA component as the template. Despite recent structural characterizations of human and Te...

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Detalles Bibliográficos
Autores principales: Wan, Futang, Ding, Yongbo, Zhang, Yuebin, Wu, Zhenfang, Li, Shaobai, Yang, Lin, Yan, Xiangyu, Lan, Pengfei, Li, Guohui, Wu, Jian, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648750/
https://www.ncbi.nlm.nih.gov/pubmed/34782750
http://dx.doi.org/10.1038/s41422-021-00586-7