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Quantitative prediction of conditional vulnerabilities in regulatory and metabolic networks using PRIME

The ability of Mycobacterium tuberculosis (Mtb) to adopt heterogeneous physiological states underlies its success in evading the immune system and tolerating antibiotic killing. Drug tolerant phenotypes are a major reason why the tuberculosis (TB) mortality rate is so high, with over 1.8 million dea...

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Detalles Bibliográficos
Autores principales: Immanuel, Selva Rupa Christinal, Arrieta-Ortiz, Mario L., Ruiz, Rene A., Pan, Min, Lopez Garcia de Lomana, Adrian, Peterson, Eliza J. R., Baliga, Nitin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648758/
https://www.ncbi.nlm.nih.gov/pubmed/34873198
http://dx.doi.org/10.1038/s41540-021-00205-6