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NF-κB activation impedes the transdifferentiation of hypertrophic chondrocytes at the growth plate of mouse embryos in diabetic pregnancy

BACKGROUND: Diabetes mellitus could cause numerous complications and health problems including abnormality of endochondral bone formation during embryogenesis. However, the underlying mechanisms still remain obscure. METHODS: Streptozotoci (STZ) was injected to induce pregestational diabetes mellitu...

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Detalles Bibliográficos
Autores principales: Liu, Xi, Qian, Fan, Fan, Qiwei, Lin, Li, He, Meiyao, Li, Peizhi, Cai, Hongmei, Ma, Lisha, Cheng, Xin, Yang, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648796/
https://www.ncbi.nlm.nih.gov/pubmed/34934622
http://dx.doi.org/10.1016/j.jot.2021.10.009