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Carbonic anhydrase inhibitor induces otic hair cell apoptosis via an intrinsic pathway and ER stress in zebrafish larvae

Carbonic anhydrase (CA) catalyzes reversible hydration of CO(2) to HCO(3)(−) to mediate pH and ion homeostasis. Some chemical pollutants have been reported to have inhibitory effects on fish CA. In this study, we investigated effects of a CA inhibitor ethoxyzolamide (EZA) on neuromasts development d...

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Detalles Bibliográficos
Autores principales: Matsumoto, Hiroko, Miyagi, Hisako, Nakamura, Nobuhiro, Shiga, Yasuhiro, Ohta, Toshihiro, Fujiwara, Shoko, Tsuzuki, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648832/
https://www.ncbi.nlm.nih.gov/pubmed/34926172
http://dx.doi.org/10.1016/j.toxrep.2021.11.018