Functional consequences of TCF4 missense substitutions associated with Pitt-Hopkins syndrome, mild intellectual disability, and schizophrenia

Transcription factor 4 (TCF4) is a basic helix-loop-helix transcription factor essential for neurocognitive development. The aberrations in TCF4 are associated with neurodevelopmental disorders including schizophrenia, intellectual disability, and Pitt-Hopkins syndrome, an autism-spectrum disorder c...

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Detalles Bibliográficos
Autores principales: Sirp, Alex, Roots, Kaisa, Nurm, Kaja, Tuvikene, Jürgen, Sepp, Mari, Timmusk, Tõnis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648840/
https://www.ncbi.nlm.nih.gov/pubmed/34748727
http://dx.doi.org/10.1016/j.jbc.2021.101381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648840/
https://www.ncbi.nlm.nih.gov/pubmed/34748727
http://dx.doi.org/10.1016/j.jbc.2021.101381

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