Cargando…

Sphingomyelin synthases 1 and 2 exhibit phosphatidylcholine phospholipase C activity

Many studies have confirmed the enzymatic activity of a mammalian phosphatidylcholine (PC) phospholipase C (PLC) (PC-PLC), which produces diacylglycerol (DAG) and phosphocholine through the hydrolysis of PC in the absence of ceramide. However, the protein(s) responsible for this activity have never...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiang, Yeun-po, Li, Zhiqiang, Chen, Yang, Cao, Yu, Jiang, Xian-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648842/
https://www.ncbi.nlm.nih.gov/pubmed/34774525
http://dx.doi.org/10.1016/j.jbc.2021.101398