The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics

Histology plays an essential role in therapeutic decision-making for lung cancer patients. However, the molecular determinants of lung cancer histology are largely unknown. We conduct whole-exome sequencing and microarray profiling on 19 micro-dissected tumor regions of different histologic subtypes...

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Detalles Bibliográficos
Autores principales: Tang, Ming, Abbas, Hussein A., Negrao, Marcelo V., Ramineni, Maheshwari, Hu, Xin, Hubert, Shawna Marie, Fujimoto, Junya, Reuben, Alexandre, Varghese, Susan, Zhang, Jianhua, Li, Jun, Chow, Chi-Wan, Mao, Xizeng, Song, Xingzhi, Lee, Won-Chul, Wu, Jia, Little, Latasha, Gumbs, Curtis, Behrens, Carmen, Moran, Cesar, Weissferdt, Annikka, Lee, J. Jack, Sepesi, Boris, Swisher, Stephen, Cheng, Chao, Kurie, Jonathan, Gibbons, Don, Heymach, John V., Wistuba, Ignacio I., Futreal, P. Andrew, Kalhor, Neda, Zhang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648877/
https://www.ncbi.nlm.nih.gov/pubmed/34873156
http://dx.doi.org/10.1038/s41467-021-27341-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648877/
https://www.ncbi.nlm.nih.gov/pubmed/34873156
http://dx.doi.org/10.1038/s41467-021-27341-1

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