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Monitoring the binding and insertion of a single transmembrane protein by an insertase

Cells employ highly conserved families of insertases and translocases to insert and fold proteins into membranes. How insertases insert and fold membrane proteins is not fully known. To investigate how the bacterial insertase YidC facilitates this process, we here combine single-molecule force spect...

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Detalles Bibliográficos
Autores principales: Laskowski, Pawel R., Pluhackova, Kristyna, Haase, Maximilian, Lang, Brian M., Nagler, Gisela, Kuhn, Andreas, Müller, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648943/
https://www.ncbi.nlm.nih.gov/pubmed/34873152
http://dx.doi.org/10.1038/s41467-021-27315-3