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LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24

LncRNA PVT1 has been implicated in numerous pathophysiological processes and diseases, especially cancers. However, the role and mechanism of PVT1 in the tumorigenesis of glioblastoma remain unclear. We investigated the alteration of PVT1 and its key functions in glioblastoma. PVT1 was upregulated a...

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Detalles Bibliográficos
Autores principales: Lv, Tao, Jin, Yichao, Miao, Yifeng, Xu, Tianqi, Jia, Feng, Feng, Haizhong, Zhang, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649109/
https://www.ncbi.nlm.nih.gov/pubmed/34938610
http://dx.doi.org/10.1016/j.omtn.2021.11.012