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Atomistic level characterisation of ssDNA translocation through the E. coli proteins CsgG and CsgF for nanopore sequencing

Two proteins of the Escherichia coli membrane protein complex, CsgG and CsgF, are studied as proteinaceous nanopores for DNA sequencing. It is highly desirable to control the DNA as it moves through the pores, this requires characterisation of DNA translocation and subsequent optimization of the por...

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Detalles Bibliográficos
Autores principales: Rattu, Punam, Glencross, Flo, Mader, Sophie L., Skylaris, Chris-Kriton, Matthews, Stephen J., Rouse, Sarah L., Khalid, Syma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649110/
https://www.ncbi.nlm.nih.gov/pubmed/34938416
http://dx.doi.org/10.1016/j.csbj.2021.11.014