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Combination of Antioxidant Enzyme Overexpression and N‐Acetylcysteine Treatment Enhances the Survival of Bone Marrow Mesenchymal Stromal Cells in Ischemic Limb in Mice With Type 2 Diabetes

BACKGROUND: Therapy with mesenchymal stem cells remains a promising but challenging approach to critical limb ischemia in diabetes because of the dismal cell survival. METHODS AND RESULTS: Critical limb ischemia in type 2 diabetes mouse model was used to explore the impact of diabetic limb ischemia...

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Detalles Bibliográficos
Autores principales: Zhu, Qiang, Hao, Hong, Xu, Huifang, Fichman, Yosef, Cui, Yuqi, Yang, Chunlin, Wang, Meifang, Mittler, Ron, Hill, Michael A., Cowan, Peter J., Zhang, Guangsen, He, Xiaoming, Zhou, Shenghua, Liu, Zhenguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649154/
https://www.ncbi.nlm.nih.gov/pubmed/34569277
http://dx.doi.org/10.1161/JAHA.121.023491