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Combination of Antioxidant Enzyme Overexpression and N‐Acetylcysteine Treatment Enhances the Survival of Bone Marrow Mesenchymal Stromal Cells in Ischemic Limb in Mice With Type 2 Diabetes
BACKGROUND: Therapy with mesenchymal stem cells remains a promising but challenging approach to critical limb ischemia in diabetes because of the dismal cell survival. METHODS AND RESULTS: Critical limb ischemia in type 2 diabetes mouse model was used to explore the impact of diabetic limb ischemia...
Autores principales: | Zhu, Qiang, Hao, Hong, Xu, Huifang, Fichman, Yosef, Cui, Yuqi, Yang, Chunlin, Wang, Meifang, Mittler, Ron, Hill, Michael A., Cowan, Peter J., Zhang, Guangsen, He, Xiaoming, Zhou, Shenghua, Liu, Zhenguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649154/ https://www.ncbi.nlm.nih.gov/pubmed/34569277 http://dx.doi.org/10.1161/JAHA.121.023491 |
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