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Angiotensin II Disrupts Neurovascular Coupling by Potentiating Calcium Increases in Astrocytic Endfeet

BACKGROUND: Angiotensin II (Ang II), a critical mediator of hypertension, impairs neurovascular coupling. Since astrocytes are key regulators of neurovascular coupling, we sought to investigate whether Ang II impairs neurovascular coupling through modulation of astrocytic Ca(2+) signaling. METHODS A...

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Detalles Bibliográficos
Autores principales: Boily, Michaël, Li, Lin, Vallerand, Diane, Girouard, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649296/
https://www.ncbi.nlm.nih.gov/pubmed/34459216
http://dx.doi.org/10.1161/JAHA.120.020608