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Spironolactone Reduces Aortic Stiffness in Patients With Resistant Hypertension Independent of Blood Pressure Change

BACKGROUND: Aortic stiffness is an independent predictor of cardiovascular events in patients with arterial hypertension. Resistant hypertension is often linked to hyperaldosteronism and associated with adverse outcomes. Spironolactone, a mineralocorticoid receptor antagonist, has been shown to redu...

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Detalles Bibliográficos
Autores principales: Aryal, Sudeep R., Siddiqui, Mohammed, Sharifov, Oleg F., Coffin, Megan D., Zhang, Bin, Gaddam, Krishna K., Gupta, Himanshu, Denney, Thomas S., Dell'Italia, Louis J., Oparil, Suzanne, Calhoun, David A., Lloyd, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649301/
https://www.ncbi.nlm.nih.gov/pubmed/34459249
http://dx.doi.org/10.1161/JAHA.120.019434